{"product_id":"recombinant-rat-csf-1-m-csf-protein-rp01847","title":"Recombinant Rat CSF-1\/M-CSF Protein - RP01847","description":"\u003cp\u003eRecombinant Rat CSF-1\/M-CSF Protein\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20ug, 50ug, 100ug\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RP01847-20, RP01847-50, RP01847-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Recombinant Rat CSF-1\/M-CSF Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Met1-Ser255) of Rat CSF-1\/M-CSF (Accession #NP_076471.3 ) fused with a His tag at the C-terminus.\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: Macrophage colony-stimulating factor 1, CSF-1, MCSF, Proteoglycan macrophage colony-stimulating factor, PG-M-CSF, Cleaved into: Processed macrophage colony-stimulating factor 1, Macrophage colony-stimulating factor 1 43 kDa subunit, Csf1, Csfm\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q8JZQ0\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 78965\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Rat\u003c\/p\u003e\n\n\u003cp\u003ePurity: ≥ 95 % as determined by SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Macrophage colony-stimulating factor (M-CSF), also known as colony-stimulating factor-1 (CSF-1), is a hemopoietic growth factor that regulates the survival, proliferation, differentiation and function of the cells of the mononuclear phagocyte lineage. M-CSF is produced by a variety of cell types and acts both locally and humorally in an autocrine and paracrine manner. Through differential mRNA splicing and posttranslational proteolytic processing and modification, M-CSF is expressed in three biologically-active isoforms: a secreted glycoprotein; a secreted proteoglycan; and a membrane spanning cell-surface glycoprotein.\u003c\/p\u003e\n\n\u003cp\u003eBio-Activity: Measured in a cell proliferation assay using M-NFS-60 mouse myelogenous leukemia lymphoblast cells. The ED50 for this effect is 5.63-22.51 ng\/mL, corresponding to a specific activity of 4.44×10^4 ~1.78×10^5 units\/mg.\u003c\/p\u003e\n\n\u003cp\u003eSource: HEK293 cells\u003c\/p\u003e\n\n\u003cp\u003eTag: C-His\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.\u003c\/p\u003e\n\n\u003cp\u003eAntigen Sequence: PSSTWMGSRLLLVCLLVSRSVAEVSEHCSHMIGNGHLQILQQLIDSQMETACLIEYKFVDQEQLDDPVCYLKKAFVLVQVIIEETMRFKDNTPNANATERLQELSMKLNSCFIKDYKEQNEACVQTYKESPLRLLEKIKNFFNETKNFLEKDWNIFSKNCNDSFAKCSSRDVVTKPDCNCLYPKATPSSDLASASPHQPPAPSMAPLADLAWDDSQRTEGSSLLPSDLPLRIEDPGSAKQRPPRS\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 0.1 EU\/μg of the protein by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"20ug","offer_id":45198385381555,"sku":"RP01847-20","price":210.0,"currency_code":"CAD","in_stock":true},{"title":"50ug","offer_id":45198385414323,"sku":"RP01847-50","price":350.0,"currency_code":"CAD","in_stock":true},{"title":"100ug","offer_id":45198385447091,"sku":"RP01847-100","price":560.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_b41a1e04-6a3a-4a06-baeb-74698bc6e00c.png?v=1766961536","url":"https:\/\/afsbio.com\/products\/recombinant-rat-csf-1-m-csf-protein-rp01847","provider":"AFSBio Inc.","version":"1.0","type":"link"}