{"product_id":"recombinant-rat-cystatin-c-cst3-protein-rp01668","title":"Recombinant Rat Cystatin-C\/CST3 Protein - RP01668","description":"\u003cp\u003eRecombinant Rat Cystatin-C\/CST3 Protein\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10ug, 20g, 50ug, 100ug\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RP01668-10, RP01668-20, RP01668-50, RP01668-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Recombinant Rat Cystatin-C\/CST3 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gly 21-Ala140) of rat Cystatin-C\/CST3 (Accession #NP_036969.1) fused with and a 6×His tag at the C-terminus.\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: CYSC; Cystatin-C; CST3\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P14841\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 25307\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Rat\u003c\/p\u003e\n\n\u003cp\u003ePurity: ≥ 90 % as determined by SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20 ℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Cystatin C, also known as Cystatin-3 (CST3) is a secreted type 2 cysteine protease inhibitor synthesized in all nucleated cells, has been proposed as a replacement for serum creatinine for the assessment of renal function, particularly to detect small reductions in glomerular filtration rate.\u003c\/p\u003e\n\n\u003cp\u003eBio-Activity: Measured by its ability to inhibit papain cleavage of a fluorogenic peptide substrate Z-FR-AMC (Catalog # ES009). The IC50 value is \u0026lt;3.4 nM, under the described conditions.\u003c\/p\u003e\n\n\u003cp\u003eSource: HEK293 cells\u003c\/p\u003e\n\n\u003cp\u003eTag: C-6His\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.22 μm filtered solution of 20mM HEPES and 150 mM NaCl, pH 7.0\u003c\/p\u003e\n\n\u003cp\u003eAntigen Sequence: GTSRPPPRLLGAPQEADASEEGVQRALDFAVSEYNKGSNDAYHSRAIQVVRARKQLVAGINYYLDVEMGRTTCTKSQTNLTNCPFHDQPHLMRKALCSFQIYSVPWKGTHTLTKSSCKNA\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 0.1 EU\/μg of the protein by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"10ug","offer_id":45198328201395,"sku":"RP01668-10","price":168.0,"currency_code":"CAD","in_stock":true},{"title":"20ug","offer_id":45198328234163,"sku":"RP01668-20","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"50ug","offer_id":45198328266931,"sku":"RP01668-50","price":420.0,"currency_code":"CAD","in_stock":true},{"title":"100ug","offer_id":45198328299699,"sku":"RP01668-100","price":672.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_e5197423-8d3e-446d-b1ab-b0c72fa65638.png?v=1766960642","url":"https:\/\/afsbio.com\/products\/recombinant-rat-cystatin-c-cst3-protein-rp01668","provider":"AFSBio Inc.","version":"1.0","type":"link"}