{"product_id":"recombinant-rat-il-4r-alpha-cd124-protein-rp01567","title":"Recombinant Rat IL-4R alpha\/CD124 Protein - RP01567","description":"\u003cp\u003eRecombinant Rat IL-4R alpha\/CD124 Protein\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10ug, 20ug, 50ug\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RP01567-10, RP01567-20, RP01567-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Recombinant Rat IL-4R alpha\/CD124 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ile26-Arg232) of rat IL-4RA\/CD124 (Accession #NP_596871.2) fused with a 6×His tag at the C-terminus.\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: CD124, IL-4RA, IL4RA, IL4R\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q63257\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 25084\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Rat\u003c\/p\u003e\n\n\u003cp\u003ePurity: ≥ 95 % as determined by SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This protein is alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells.\u003c\/p\u003e\n\n\u003cp\u003eSource: HEK293 cells\u003c\/p\u003e\n\n\u003cp\u003eTag: C-His\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.\u003c\/p\u003e\n\n\u003cp\u003eAntigen Sequence: IKVLGDPTCFSDYIRTSTCEWQLDSTVDCSSQLLLDYRLLFEFSENLTCTPKNSADTVCVCQMAIEEPIQADTYWLELWSERGQLWQGSFKPSDNVKPPAPDNLTLHTNVSNALLLMWSNPYPSNNFLHKGLICMVNISREDNPAEFKVYNVTYTEPKLSFPVNTLTSGVRYRARVRVLSQSFPGIWSEWSPSITWYNHFQLPLLQR\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1 EU\/μg of the protein by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"10ug","offer_id":45198369620147,"sku":"RP01567-10","price":196.0,"currency_code":"CAD","in_stock":true},{"title":"20ug","offer_id":45198369652915,"sku":"RP01567-20","price":266.0,"currency_code":"CAD","in_stock":true},{"title":"50ug","offer_id":45198369685683,"sku":"RP01567-50","price":280.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_1834556e-629a-4eec-9b9b-6fe2326d8fce.png?v=1766961307","url":"https:\/\/afsbio.com\/products\/recombinant-rat-il-4r-alpha-cd124-protein-rp01567","provider":"AFSBio Inc.","version":"1.0","type":"link"}