{"product_id":"recombinant-rat-il-5-protein-rp01849","title":"Recombinant Rat IL-5 Protein - RP01849","description":"\u003cp\u003eRecombinant Rat IL-5 Protein\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10ug, 20g, 50ug, 100ug\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RP01849-10, RP01849-20, RP01849-50, RP01849-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eDescription: Recombinant Rat IL-5 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Met20-Val132) of Rat IL-5 (Accession #NP_068606.1 ) fused with a His tag at the C-terminus.\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: Interleukin-5, IL-5, B-cell growth factor II, BCGF-II, Cytotoxic T-lymphocyte inducer, Eosinophil differentiation factor, T-cell replacing factor, TRF, Il5, Il-5\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q08125\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 24497\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Rat\u003c\/p\u003e\n\n\u003cp\u003ePurity: ≥ 85% as determined by SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20 ℃. Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Interleukin-5 (IL-5), which is produced primarily by type 2 T helper lymphocytes (Th2), is an eosinophil differentiation and activation factor. Antagonism of IL-5 activity is being explored as a potential treatment of a number of disease conditions associated with eosinophils in animal models. Interleukin-5 (IL-5) which was previously named T cell replacing factor, B cell growth and differentiation factor, colony forming unit growth stimulating factor and eosinophil differentiation factor is produced predominantly by T cells.\u003c\/p\u003e \n\n\u003cp\u003eBio-Activity: Measured in a cell proliferation assay using TF-1 Human erythroleukemic cells. The ED50 for this effect is 0.695-2.78 ng\/mL, corresponding to a specific activity of 3.60×10^5 ~1.44×10^6 units\/mg.\u003c\/p\u003e\n\n\u003cp\u003eSource: HEK293 cells\u003c\/p\u003e\n\n\u003cp\u003eTag: C-His\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.\u003c\/p\u003e\n\n\u003cp\u003eAntigen Sequence: MEIPMSTVVKETLIQLSTHRALLTSNETMRLPVPTHKNHQLCIGEIFQGLDILKNQTVRGGTVEILFQNLSLIKKYIDGQKEKCGEERRKTRHFLDYLQEFLGVMSTEWAMEV\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 0.1 EU\/μg of the protein by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"10ug","offer_id":45198340587699,"sku":"RP01849-10","price":168.0,"currency_code":"CAD","in_stock":true},{"title":"20ug","offer_id":45198340620467,"sku":"RP01849-20","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"50ug","offer_id":45198340653235,"sku":"RP01849-50","price":420.0,"currency_code":"CAD","in_stock":true},{"title":"100ug","offer_id":45198340686003,"sku":"RP01849-100","price":672.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_4b613561-723c-4492-9b40-c06b041c1e68.png?v=1766960796","url":"https:\/\/afsbio.com\/products\/recombinant-rat-il-5-protein-rp01849","provider":"AFSBio Inc.","version":"1.0","type":"link"}