{"product_id":"recombinant-rat-interleukin-13-rrtil-13-pr3009","title":"Recombinant Rat Interleukin 13 (rRtIL-13) - PR3009","description":"\u003cp\u003eRecombinant Rat Interleukin 13 (rRtIL-13)\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PR3009-2, PR3009-10\u003c\/p\u003e\n\n\u003cp\u003eSizes: 2µg, 10µg\u003c\/p\u003e\n\n\u003cp\u003eSource: Escherichia coli\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: Approximately 12.1 kDa, a single non-glycosylated polypeptide chain containing 110 amino acids.\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt;95% by SDS-PAGE and HPLC analyses.\u003c\/p\u003e\n\n\u003cp\u003eBiological Activity: Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. The ED50 for this effect is typically 1-4 ng\/mL.\u003c\/p\u003e\n\n\u003cp\u003ePhysical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2mm filtered concentrated solution in PBS, pH 7.4.\u003c\/p\u003e\n\n\u003cp\u003eAA Sequence: PVRRSTSPPV ALRELIEELS NITQDQKTSL CNSSMVWSVD LTAGGFCAAL ESLTNISSCN AIHRTQRILN GLCNQKASDV ASSPPDTKIE VAQFISKLLN YSKQLFRYGH\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: Less than 1EU\/μg of rRtIL-13 as determined by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg\/mL. Stock solutions should be apportioned into working aliquots and stored at \u0026lt;-20°C. Further dilutions should be made in appropriate buffered solutions.\u003c\/p\u003e\n\n\u003cp\u003eStorage: This lyophilized preparation is stable at 2-8°C, but should be kept at -20°C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8°C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20°C to -70°C. Avoid repeated freeze\/thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eUsage: This material is offered by USA Bioworld biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE. Made in China\u003c\/p\u003e\n\n\u003cp\u003eDescription: IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and also by mast cells and NK cells. Targeted deletion of IL-13 in mice resulted in impaired Th2 cell development and indicated an important role for IL-13 in the expulsion of gastrointestinal parasites. IL-13 exerts anti-inflammatory effects on monocytes and macrophages and it inhibits the expression of inflammatory cytokines such as IL-1beta, TNF-alpha, IL-6 and IL-8. IL-13 has also been shown to enhance B cell proliferation and to induce isotype switching resulting in increased production of IgE. Blocking of IL-13 activity inhibits the pathophysiology of asthma.\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"2µg","offer_id":42882222882995,"sku":"PR3009-2","price":260.23,"currency_code":"CAD","in_stock":true},{"title":"10µg","offer_id":42882222915763,"sku":"PR3009-10","price":490.83,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_c5ec4486-0e04-448e-914f-643cc9f655f3.jpg?v=1702049552","url":"https:\/\/afsbio.com\/products\/recombinant-rat-interleukin-13-rrtil-13-pr3009","provider":"AFSBio Inc.","version":"1.0","type":"link"}