{"product_id":"recombinant-rat-interleukin-2-il-2-protein-his-tag-pdmr100011","title":"Recombinant Rat Interleukin-2\/IL-2 Protein (His Tag) - PDMR100011","description":"\u003cp\u003eRecombinant Rat Interleukin-2\/IL-2 Protein (His Tag)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μg, 100μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PDMR100011-20, PDMR100011-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: Interleukin-2; IL-2\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Aldesleukin; IL 2; IL-2; IL2; IL2; Interleukin 2; Interleukin-2; Involved in regulation of T cell clonal expansion; Lymphokine; POIL2; T Cell Growth Factor; T-cell growth factor; TCGF\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P17108\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction;; immunology\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Rat\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: HEK293 Cells\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-His\u003c\/p\u003e\n\n\u003cp\u003eAccession: P17108\u003c\/p\u003e\n\n\u003cp\u003eBackground: Interleukin-2(IL-2)is a O-glycosylated four α-helix bundle cytokine that has potent stimulatory activity for antigenactivated T cells. It is expressed by CD4+ and CD8+ T cells, γδ T cells, B cells, dendritic cells, and eosinophils. Mature rat IL-2 shares 66% and 73% amino acid sequence identity with human and mouse IL-2, respectively. The receptor for IL-2 consists of three subunits that are present on the cell surface in varying preformed complexes. IL-2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2\/IL-2R signaling is required for T-cell proliferation and other fundamental functions that are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine-activated killer cells, monocytes, macrophages and oligodendrocytes.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Ala 21-Gln 155\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from sterile PBS, pH 7.4.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: Please contact us for more information.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 14.74 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 16 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"20μg","offer_id":43083635654835,"sku":"PDMR100011-20","price":264.6,"currency_code":"CAD","in_stock":true},{"title":"100μg","offer_id":43083635687603,"sku":"PDMR100011-100","price":418.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_854779aa-1002-43c6-914c-fb7fe6aeff9f.png?v=1708945722","url":"https:\/\/afsbio.com\/products\/recombinant-rat-interleukin-2-il-2-protein-his-tag-pdmr100011","provider":"AFSBio Inc.","version":"1.0","type":"link"}