{"product_id":"recombinant-rhesus-macaque-cd27-tnfrsf7-protein-fc-tag-pksq050077","title":"Recombinant Rhesus Macaque CD27\/TNFRSF7 Protein (Fc Tag) - PKSQ050077","description":"\u003cp\u003eRecombinant Rhesus Macaque CD27\/TNFRSF7 Protein (Fc Tag)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSQ050077-10, PKSQ050077-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: CD27; TNFRSF7\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: CD27 Antigen; CD27L Receptor; T-Cell Activation Antigen CD27; T14; Tumor Necrosis Factor Receptor Superfamily Member 7; CD27; CD27; TNFRSF7\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: F7BYS2\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Rhesus macaque\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: HEK293 Cells\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: C-Fc\u003c\/p\u003e\n\n\u003cp\u003eAccession: F7BYS2\u003c\/p\u003e\n\n\u003cp\u003eBackground: CD27 antigen, also known as CD27L receptor, T-cell activation antigen CD27, T14, S152, Tp55, TNFRSF7 and Tumor necrosis factor receptor for superfamily member 7, belongs to the TNF-receptor superfamily. CD27 is a single-pass type I membrane protein and exists as a homodimer form, containing three TNFR-Cys repeats. CD27 transduces signals that lead to the activation of NF-KappaB and MAPK8\/JNK. CD27 is involved in regulating B-cell activation and immunoglobulin synthesis, binding to the ligand CD70. TRAF2 and TRAF5 have been shown to mediate the signaling process of CD27. CD27-binding protein (SIVA), which is a proapoptotic protein, can bind to CD27 and is thought to play a key role in the apoptosis. CD27 is required for generation and long-term maintenance of T cell immunity.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Thr21-Ile192\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 90 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2 μm filtered solution of 20mMTris, 150mM NaCl, pH8.5.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 46.5 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 60-90 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43072230621363,"sku":"PKSQ050077-10","price":180.6,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43072230654131,"sku":"PKSQ050077-50","price":525.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_f7ecbe65-baba-4b63-9f97-5b9875b611a8.png?v=1708684740","url":"https:\/\/afsbio.com\/products\/recombinant-rhesus-macaque-cd27-tnfrsf7-protein-fc-tag-pksq050077","provider":"AFSBio Inc.","version":"1.0","type":"link"}