{"product_id":"recombinant-s100a4-monoclonal-antibody-e-ab-81606","title":"Recombinant S100A4 Monoclonal Antibody - E-AB-81606","description":"\u003cp\u003eRecombinant S100A4 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-81606-50, E-AB-81606-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: S100A4\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: 18A2; 42A; calcium Placental protein; Calvasculin; CAPL; Fibroblast specific protein 1 (FSP1); Fibroblast specific protein 1; Fibroblast specific protein; FSP1; Leukemia multidrug resistance associated protein; Malignant transformation suppression 1 (MTS1); Malignant transformation suppression 1; Metastasin; MTS1; OTTHUMP00000015467; OTTHUMP00000015468; P9KA; PEL98; Placental calcium-binding protein; Protein Mts1; Protein S100 A4; Protein S100-A4; S100 calcium binding protein A4 (calcium protein; calvasculin; metastasin; murine placental homolog); S100 calcium binding protein A4; S100 calcium-binding protein A4; S100a4; S10A4\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Cardiovascular, Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB, IHC-P, IF\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Rabbit Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone No.: R01-7H1\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P26447\u003c\/p\u003e\n\n\u003cp\u003eBackground: S100A4 is a member of the S100 family of calcium-binding proteins. The S100 family members have been involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100A4 is known to localize to and function in the nucleus, cytoplasm of cells and the extracellular space. S100A4 has also been shown to be associated with tumor growth, motility, invasion, metastasis, angiogenesis, apoptosis and chemoresistance. It is a fibroblast-specific protein associated with mesenchymal cell morphology and motility, is expressed during epithelial-mesenchymal transformations (EMT) in vivo. It is an improved marker for lung fibroblasts that could be useful for investigating the pathogenesis of pulmonary fibrosis. Overexpression of S100A4 is correlated with a worse prognosis inpatients with various types of cancer.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 300 μg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: A synthetic peptide of human S100A4\u003c\/p\u003e\n\n\u003cp\u003eBuffer: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity Purified\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:1000-1:2000 IHC 1:50-1:100\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 12kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 12kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"50μL","offer_id":43149041041587,"sku":"E-AB-81606-50","price":224.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":43149041074355,"sku":"E-AB-81606-100","price":364.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_57e898c0-e394-4239-92a4-6952a9935ef3.png?v=1710339016","url":"https:\/\/afsbio.com\/products\/recombinant-s100a4-monoclonal-antibody-e-ab-81606","provider":"AFSBio Inc.","version":"1.0","type":"link"}