{"product_id":"recombinant-stat5b-monoclonal-antibody-e-ab-81513","title":"Recombinant STAT5b Monoclonal Antibody - E-AB-81513","description":"\u003cp\u003eRecombinant STAT5b Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-81513-50, E-AB-81513-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: STAT5b\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: STAT5; STAT5B\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Epigenetics and Nuclear Signaling, Metabolism, Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB, IHC-P\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Rabbit Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone No.: R08-2I8\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P51692\u003c\/p\u003e\n\n\u003cp\u003eBackground: STAT5B belongs to the transcription factor STAT family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. STAT5B carries out a dual function: signal transduction and activation of transcription. STAT5B mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 300 μg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant protein of human STAT5b\u003c\/p\u003e\n\n\u003cp\u003eBuffer: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity Purified\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:1000-1:2000 IHC 1:50-1:100\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 90kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 90kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"50μL","offer_id":43149029998771,"sku":"E-AB-81513-50","price":224.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":43149030031539,"sku":"E-AB-81513-100","price":364.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_99586378-67bc-4969-a1db-7555bc21d356.png?v=1710338748","url":"https:\/\/afsbio.com\/products\/recombinant-stat5b-monoclonal-antibody-e-ab-81513","provider":"AFSBio Inc.","version":"1.0","type":"link"}