{"product_id":"recombinant-swine-ifn-gamma-proteinn-hisactive-pkss000012","title":"Recombinant Swine IFN gamma protein(N-His)(active) - PKSS000012","description":"\u003cp\u003eRecombinant Swine IFN gamma protein(N-His)(active)\u003c\/p\u003e\n\n\u003cp\u003eSizes: 5μg, 20μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSS000012-5, PKSS000012-20\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: IFN gamma\u003c\/p\u003e\n\n\u003cp\u003eTarget Symptom: IFN-gamma; IFNG\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Porcine\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: E.coli\u003c\/p\u003e\n\n\u003cp\u003eApplication: Cell culture\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: N-His\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P17803\u003c\/p\u003e\n\n\u003cp\u003eAccession: P17803\u003c\/p\u003e\n\n\u003cp\u003eBackground: IFNγ is the major interferon produced by mitogenically or antigenically stimulated lymphocytes. It is structurally different from type I interferon and its major activity is immunoregulation. It has been implicated in the expression of class II histocompatibility antigens in cells that do not normally produce them; leading to autoimmune disease. Interferon gamma is produced mainly byT-cells and natural killer cells activated by antigens; mitogens; or alloantigens. It is produced by lymphocytes expressing the surface antigens CD4 and CD8. IFNγ synthesis is induced by IL-2; FGF-basic; and EGF.\u003c\/p\u003e\n\n\u003cp\u003eActivity: Measure by its ability to protect PK15 cells infected with encephalomyocarditis (EMC) virus. The ED50 for this effect is \u0026lt; 40 pg\/mL.\u003c\/p\u003e\n\n\u003cp\u003eSequence: MSYTTYFLAFQLCVTLCFSGSYCQAPFFKEITILKDYFNASTSDVPNGGPLFLEILKNWKEESDKKIIQSQIVSFYFKFFEIFKDNQAIQRSMDVIKQDMFQRFLNGSSGKLNDFEKLIKIPVDNLQIQRKAISELIKVMNDLSPRSNLRKRKRSQTMFQGQRASK\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from sterile PBS, pH 7.4\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: Please contact us for more information.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 20.25 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"5μg","offer_id":43118189215923,"sku":"PKSS000012-5","price":277.2,"currency_code":"CAD","in_stock":true},{"title":"20μg","offer_id":43118189248691,"sku":"PKSS000012-20","price":693.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_2316aad2-fac6-4ac4-809c-f9c8dffb0ac2.png?v=1709637781","url":"https:\/\/afsbio.com\/products\/recombinant-swine-ifn-gamma-proteinn-hisactive-pkss000012","provider":"AFSBio Inc.","version":"1.0","type":"link"}