{"product_id":"recombinant-trailr-2-human-bk0333","title":"Recombinant TRAILR-2, Human - BK0333","description":"\u003cp\u003eRecombinant TRAILR-2, Human\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BK0333-10, BK0333-50\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eSource: HEK 293\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: ~15 kDa, observed by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95% as analyzed by SDS-PAGE and HPLC.\u003c\/p\u003e\n\n\u003cp\u003eBiological Activity: ED50 \u0026lt; 6 ng\/ml, measured in a cell proliferation assay using RPMI-8226 cells in the presence of 25 ng\/ml of human TRAIL.\u003c\/p\u003e\n\n\u003cp\u003ePhysical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized after extensive dialysis against PBS.\u003c\/p\u003e\n\n\u003cp\u003eAA Sequence: ALITQQDLAPQQRAAPQQKRSSPSEGLCPPGHHISEDGRDCISCKYGQDYSTHWNDLLFCLRCTRCDSGEVELSPCTTTR\u003cbr\u003e\n Nt VCQCEEGTFREEDSPEMCRKCRTGCPRGMVKVGDCTPWSDIECVHKE\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 0.2 EU\/μg, determined by LAL method.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Reconstituted in ddH2O or PBS at 100 μg\/ml.\u003c\/p\u003e\n\n\u003cp\u003eStorage: Lyophilized recombinant Human TRAIL Receptor-2 remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, Human TRAIL Receptor-2 should be stable up to 1 week at 4°C or up to 2 months at -20°C.\u003c\/p\u003e\n\n\u003cp\u003eUsage: This material is offered by USA Bioworld biotech for research, laboratory or further evaluation purposes. For research use only.\u003c\/p\u003e\n\n\u003cp\u003eDescription: TRAIL Receptor-2 is a cell-surface receptor involved in tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced cell-death signaling. The death ligand TRAIL bears high potential as a new anticancer agent, as binding to the death receptors TRAIL-R1 or TRAIL-R2 triggers apoptosis in most cancer cells. TRAIL-R2 is associated with a decrease in the survival rates of breast cancer patients.\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"10μg","offer_id":42882263908531,"sku":"BK0333-10","price":217.41,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":42882263941299,"sku":"BK0333-50","price":375.54,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_d86e4e95-33b4-4a37-86f3-e717af548e24.jpg?v=1702050329","url":"https:\/\/afsbio.com\/products\/recombinant-trailr-2-human-bk0333","provider":"AFSBio Inc.","version":"1.0","type":"link"}