{"product_id":"recombinant-vibrio-cholerae-toxin-b-protein-pksq050090","title":"Recombinant Vibrio cholerae Toxin B Protein - PKSQ050090","description":"\u003cp\u003eRecombinant Vibrio cholerae Toxin B Protein\u003c\/p\u003e\n\n\u003cp\u003eSizes: 10μg, 50μg\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: PKSQ050090-10, PKSQ050090-50\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: Choleragenoid; CTXB; toxB\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: Cholera enterotoxin subunit B; Cholera enterotoxin B chain; Cholera enterotoxin gamma chain; Choleragenoid; ctxB; toxB\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P01556\u003c\/p\u003e\n\n\u003cp\u003eTarget Species: Vibrio cholerae\u003c\/p\u003e\n\n\u003cp\u003eExpression Host: E.coli\u003c\/p\u003e\n\n\u003cp\u003eFusion Tag: None\u003c\/p\u003e\n\n\u003cp\u003eAccession: P01556\u003c\/p\u003e\n\n\u003cp\u003eBackground: Cholera toxin is protein complex secreted by the bacterium Vibrio cholerae. It is responsible for the massive, watery diarrhea characteristic of cholera infection. Cholera enterotoxin subunit B (CTXB) pentameric ring directs the A subunit to its target by binding to the GM1 gangliosides present on the surface of the intestinal epithelial cells. It can bind five GM1 gangliosides. It has no toxic activity by itself.\u003c\/p\u003e\n\n\u003cp\u003eSequence: Thr22-Asn124\u003c\/p\u003e\n\n\u003cp\u003ePurity: \u0026gt; 95 % as determined by reducing SDS-PAGE.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Lyophilized from a 0.2 μm filtered solution of 50mM Tris, 200mM NaCl, pH8.0.\u003cbr\u003e\nNormally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.\u003cbr\u003e\nPlease refer to the specific buffer information in the printed manual.\u003c\/p\u003e\n\n\u003cp\u003eReconstitution: Please refer to the printed manual for detailed information.\u003c\/p\u003e\n\n\u003cp\u003eEndotoxin: \u0026lt; 1.0 EU per μg of the protein as determined by the LAL method.\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 11.8 kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 11 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20℃ for 3 months.\u003c\/p\u003e\n\n\u003cp\u003eShipping: This product is provided as lyophilized powder which is shipped with ice packs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"10μg","offer_id":43072231801011,"sku":"PKSQ050090-10","price":249.2,"currency_code":"CAD","in_stock":true},{"title":"50μg","offer_id":43072231833779,"sku":"PKSQ050090-50","price":732.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_ecd68099-7446-4c66-af27-8565f096a8f6.png?v=1708684780","url":"https:\/\/afsbio.com\/products\/recombinant-vibrio-cholerae-toxin-b-protein-pksq050090","provider":"AFSBio Inc.","version":"1.0","type":"link"}