{"product_id":"recombinant-wnt5a-monoclonal-antibody-e-ab-81621","title":"Recombinant Wnt5a Monoclonal Antibody - E-AB-81621","description":"\u003cp\u003eRecombinant Wnt5a Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-81621-50, E-AB-81621-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: Wnt5a\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: hWNT5A; Wnt5a; WNT5A\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Neuroscience, Stem Cells\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB, IF\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Rabbit Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone No.: R08-4A3\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P41221\u003c\/p\u003e\n\n\u003cp\u003eBackground: The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene encodes a member of the WNT family that signals through both the canonical and non-canonical WNT pathways. This protein is a ligand for the seven transmembrane receptor frizzled-5 and the tyrosine kinase orphan receptor 2. This protein plays an essential role in regulating developmental pathways during embryogenesis. This protein may also play a role in oncogenesis. Mutations in this gene are the cause of autosomal dominant Robinow syndrome. Alternate splicing results in multiple transcript variants.WNT5A (Wnt Family Member 5A) is a Protein Coding gene. Diseases associated with WNT5A include Robinow Syndrome, Autosomal Dominant 1 and Autosomal Dominant Robinow Syndrome. Among its related pathways are Validated targets of C-MYC transcriptional repression and Wnt Signaling Pathways: beta-Catenin-independent Wnt\/Ca2+ Signaling and Other Non-canonical Wnt Signaling Pathways. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and protein domain specific binding. An important paralog of this gene is WNT5B.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 300 μg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: A synthetic peptide of human Wnt5a\u003c\/p\u003e\n\n\u003cp\u003eBuffer: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity Purified\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:1000 IF 1:50-1:100\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 42kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 45kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"50μL","offer_id":43149042188467,"sku":"E-AB-81621-50","price":224.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":43149042221235,"sku":"E-AB-81621-100","price":364.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_f1adf1f1-38b3-4559-873c-49d97b69af1c.png?v=1710339055","url":"https:\/\/afsbio.com\/products\/recombinant-wnt5a-monoclonal-antibody-e-ab-81621","provider":"AFSBio Inc.","version":"1.0","type":"link"}