{"product_id":"repetin-rabbit-pab-es4722","title":"Repetin rabbit pAb - ES4722","description":"\u003cp\u003eRepetin rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES4722-50, ES4722-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: domain:Can be divided into a N-terminal domain with significant homology to S100-like calcium-binding proteins, a central domain containing a series of short tandem repeats, and two flanking segments with low homology to the consensus sequences of the central repeats., function:Involved in the cornified cell envelope formation. Multifunctional epidermal matrix protein. Reversibly binds calcium., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., PTM:Potential substrate of transglutaminase. Some arginines are probably converted to citrullines by peptidylarginine deimidase., similarity:Belongs to the S100-fused protein family., similarity:Contains 2 EF-hand domains., tissue specificity:Expression is scattered in the normal epidermis but strong in the acrosyringium, the inner hair root sheat and in the filiform papilli of the tongue.,\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: RPTN; Repetin\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IHC\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-2000; IHC-p 1:50-300\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Rat; Mouse;\u003c\/p\u003e \n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human RPTN. AA range:648-697\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 90kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 126638\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: Q6XPR3\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Secreted, extracellular space, extracellular matrix.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202212552883,"sku":"ES4722-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202212585651,"sku":"ES4722-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_54f7da35-9f01-4cb5-bac6-97af89b96e2d.png?v=1767124333","url":"https:\/\/afsbio.com\/products\/repetin-rabbit-pab-es4722","provider":"AFSBio Inc.","version":"1.0","type":"link"}