{"product_id":"rfa1-rabbit-pab-es20438","title":"RFA1 rabbit pAb - ES20438","description":"\u003cp\u003eRFA1 rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES20438-50, ES20438-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: function:It participates in a very early step in initiation. RP-A is a single-stranded DNA-binding protein. Absolutely required for simian virus 40 DNA replication in vitro., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Belongs to the replication factor A protein 1 family., subunit:Heterotrimer of 70, 32 and 14 kDa chains. The DNA-binding activity may reside exclusively on the 70 kDa subunit. Interacts with RIP and XPA. Interacts with RPA4.,\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: Replication protein A 70 kDa DNA-binding subunit (RP-A p70; Replication factor A protein 1; RF-A protein 1; Single-stranded DNA-binding protein)\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; ELISA; IHC\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Monkey; Mouse; Rat\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthesized peptide derived from human RFA1\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 6117\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: P27694\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Nucleus. Nucleus, PML body. Enriched in PML bodies in cells displaying alternative lengthening of their telomeres.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45201962270899,"sku":"ES20438-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45201962303667,"sku":"ES20438-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_404e9e94-9dd8-40df-8358-563cce4404fa.png?v=1767118936","url":"https:\/\/afsbio.com\/products\/rfa1-rabbit-pab-es20438","provider":"AFSBio Inc.","version":"1.0","type":"link"}