{"product_id":"rfox1-polyclonal-antibody-bt-ap13684","title":"RFOX1 Polyclonal Antibody - BT-AP13684","description":"\u003cp\u003eRFOX1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP13684-20, BT-AP13684-50, BT-AP13684-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The Fox-1 family of RNA-binding proteins is evolutionarily conserved, and regulates tissue-specific alternative splicing in metazoa. Fox-1 recognizes a (U)GCAUG stretch in regulated exons or in flanking introns. The protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the product of the SCA2 gene which causes familial neurodegenerative diseases. Fox-1 and ataxin-2 are both localized in the trans-Golgi network. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Developmental biology; Epigenetics and nuclear signaling; Neuroscience\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: RBFOX1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: RNA binding protein fox-1 homolog 1\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q9NWB1; Mouse: Q9JJ43\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: RNA binding protein fox-1 homolog 1;Ataxin-2-binding protein 1;Fox-1 homolog A;Hexaribonucleotide-binding protein 1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 54715\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239313236147,"sku":"BT-AP13684-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239313268915,"sku":"BT-AP13684-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239313301683,"sku":"BT-AP13684-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_888f9118-ba25-4fbb-b5c8-42d5dfc224fd.png?v=1769392930","url":"https:\/\/afsbio.com\/products\/rfox1-polyclonal-antibody-bt-ap13684","provider":"AFSBio Inc.","version":"1.0","type":"link"}