{"product_id":"rgr-polyclonal-antibody-bt-ap07796","title":"RGR Polyclonal Antibody - BT-AP07796","description":"\u003cp\u003eRGR Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP07796-20, BT-AP07796-50, BT-AP07796-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: RGR (retinal G protein coupled receptor) encodes a putative retinal G-protein coupled receptor. RGR is a member of the opsin subfamily of the 7 transmembrane, G-protein coupled receptor 1 family. Like other opsins which bind retinaldehyde, it contains a conserved lysine residue in the seventh transmembrane domain. The protein acts as a photoisomerase to catalyze the conversion of all-trans-retinal to 11-cis-retinal. The reverse isomerization occurs with rhodopsin in retinal photoreceptor cells. The protein is exclusively expressed in tissue adjacent to retinal photoreceptor cells, the retinal pigment epithelium and Mueller cells. RGR may be associated with autosomal recessive and autosomal dominant retinitis pigmentosa (arRP and adRP, respectively). Alternative splicing results in multiple transcript variants encoding different isoforms.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Others\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: RGR\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC-p, IF, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: RGR Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 31874\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P47804; Mouse: Q9Z2B3\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: RGR; RPE-retinal G protein-coupled receptor\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 5995\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239880188083,"sku":"BT-AP07796-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239880220851,"sku":"BT-AP07796-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239880253619,"sku":"BT-AP07796-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_0e8af221-7419-4067-a87f-819d28bbbdc8.png?v=1769400364","url":"https:\/\/afsbio.com\/products\/rgr-polyclonal-antibody-bt-ap07796","provider":"AFSBio Inc.","version":"1.0","type":"link"}