{"product_id":"rgs7-rabbit-pab-es7042","title":"RGS7 rabbit pAb - ES7042","description":"\u003cp\u003eRGS7 rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES7042-50, ES7042-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: function:Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Activity on G (o)-alpha is specifically enhanced by the RGS6\/GNG5 dimer. May play a role in synaptic vesicle exocytosis. May play important role in the rapid regulation of neuronal excitability and the cellular responses to short-lived stimulations., PTM:Palmitoylated., PTM:Phosphorylation and subsequent interaction with 14-3-3 proteins inhibits GAP activity., similarity:Contains 1 DEP domain., similarity:Contains 1 G protein gamma domain., similarity:Contains 1 RGS domain., subunit:Heterodimer with GNG5. Interacts with RGS7BP, leading to regulate the subcellular location of the heterodimer formed with Gbeta5 (By similarity). Interacts with 14-3-3 protein Tau and SNAP25BP.,\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: RGS7; Regulator of G-protein signaling 7; RGS7\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; ELISA; IHC\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Mouse; Rat\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human RGS7. AA range:155-204\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 65kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 6000\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: P49802\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Cytoplasm, cytosol. Cytoplasm. Cell membrane. Membrane; Peripheral membrane protein; Cytoplasmic side. Interaction with PKD1 promotes location at the cell membrane (PubMed:10339594). Interaction with RGS7BP promotes location at the cell membrane (PubMed:15897264).\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202325602483,"sku":"ES7042-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202325635251,"sku":"ES7042-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_68d1982a-9963-4384-82f1-71217b3ff370.png?v=1767126631","url":"https:\/\/afsbio.com\/products\/rgs7-rabbit-pab-es7042","provider":"AFSBio Inc.","version":"1.0","type":"link"}