{"product_id":"rheb-polyclonal-antibody-bt-ap07814","title":"RHEB Polyclonal Antibody - BT-AP07814","description":"\u003cp\u003eRHEB Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP07814-20, BT-AP07814-50, BT-AP07814-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: RHEB (Ras homolog enriched in brain) is a member of the small GTPase superfamily and encodes a lipid-anchored, cell membrane protein with five repeats of the RAS-related GTP-binding region. This protein is vital in regulation of growth and cell cycle progression due to its role in the insulin\/TOR\/S6K signaling pathway. The protein has GTPase activity and shuttles between a GDP-bound form and a GTP-bound form, and farnesylation of the protein is required for this activity. Three pseudogenes have been mapped, two on chromosome 10 and one on chromosome 22.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: RHEB\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat, Cow\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: RHEB Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 20497\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q15382; Mouse: Q921J2; Rat: Q62639\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Ras homolog enriched in brain\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 6009; Mouse: 19744\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239881171123,"sku":"BT-AP07814-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239881203891,"sku":"BT-AP07814-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239881236659,"sku":"BT-AP07814-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_03d0b5f5-9f7c-4648-9d8a-7d45d86754c0.png?v=1769400379","url":"https:\/\/afsbio.com\/products\/rheb-polyclonal-antibody-bt-ap07814","provider":"AFSBio Inc.","version":"1.0","type":"link"}