{"product_id":"rho-g-polyclonal-antibody-bt-ap07827","title":"Rho G Polyclonal Antibody - BT-AP07827","description":"\u003cp\u003eRho G Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP07827-20, BT-AP07827-50, BT-AP07827-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: RHOG encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The encoded protein facilitates translocation of a functional guanine nucleotide exchange factor (GEF) complex from the cytoplasm to the plasma membrane where ras-related C3 botulinum toxin substrate 1 is activated to promote lamellipodium formation and cell migration. Two related pseudogene have been identified on chromosomes 20 and X.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: RHOG\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Rho G Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 21309\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P84095; Mouse: P84096\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: RHOG; ARHG; Rho-related GTP-binding protein RhoG\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 391; Mouse: 56212\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239881564339,"sku":"BT-AP07827-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239881597107,"sku":"BT-AP07827-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239881629875,"sku":"BT-AP07827-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_cba98657-e41e-4787-b9fa-bff716e27276.png?v=1769400384","url":"https:\/\/afsbio.com\/products\/rho-g-polyclonal-antibody-bt-ap07827","provider":"AFSBio Inc.","version":"1.0","type":"link"}