{"product_id":"rhodopsin-polyclonal-antibody-bs91170","title":"Rhodopsin Polyclonal Antibody-BS91170","description":"\u003cp\u003eRhodopsin Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS91170-50, BS91170-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P08100(Human) P51489(Rat)\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC\u003c\/p\u003e\n\n\u003cp\u003eAll Applications: WB:1:500-1:1,000\u003cbr\u003e\nIHC:1:50-1:200\u003c\/p\u003e\n\n\u003cp\u003eBackground: In aerobic respiration reactions, succinate dehydrogenase (SDH) catalyzes the oxidation of succinate and ubiquinone to fumarate and ubiquinol. Four subunits comprise the SDH protein complex: a flavochrome subunit (SDHA), an iron-sulfur protein (SDHB), and two membrane-bound subunits (SDHC and SDHD) anchored to the inner mitochondrial membrane. Mutations to these subunits cause mitochondrial dysfunction, corresponding to several distinct disorders. Mutations in the membrane bound components may cause hereditary paraganglioma, while SDHA mutations are associated with juvenile encephalopathy as well as Leigh Syndrome, a severe neurological disorder. Inactivating mutations in SDHB correlate with inherited, but not necessarily sporadic, cases of pheochromocytoma.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: ProA affinity purified\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Immunohistochemical analysis of paraffin-embedded rat retina tissue using anti-Rhodopsin antibody. Counter stained with hematoxylin.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: 39 kDa\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: Rhodopsin polyclonal antibody detects endogenous levels of Rhodopsin protein.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: RHO, CSNBAD1, MGC138309, MGC138311, OPN 2, OPN2, opsd, OPSD, opsin 2, Opsin 2 rod pigment, Opsin-2, Opsin2, Retinitis Pigmentosa 4, Retinitis pigmentosa 4 autosomal dominant, RHO, Rhodopsin, RP 4, RP4,\u003c\/p\u003e \n\n\u003cp\u003eImmunogen: recombinant protein\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42939207024819,"sku":"BS91170-50","price":415.38,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42939207057587,"sku":"BS91170-100","price":640.78,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_e3c02032-17c4-4f14-9199-808a92d00cb4.jpg?v=1704545085","url":"https:\/\/afsbio.com\/products\/rhodopsin-polyclonal-antibody-bs91170","provider":"AFSBio Inc.","version":"1.0","type":"link"}