{"product_id":"rhodopsin-polyclonal-antibody-bt-ap07833","title":"Rhodopsin Polyclonal Antibody - BT-AP07833","description":"\u003cp\u003eRhodopsin Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP07833-20, BT-AP07833-50, BT-AP07833-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Retinitis pigmentosa is an inherited progressive disease which is a major cause of blindness in western communities. It can be inherited as an autosomal dominant, autosomal recessive, or X-linked recessive disorder. In the autosomal dominant form, which comprises about 25% of total cases, approximately 30% of families have mutations in the gene encoding the rod photoreceptor-specific protein rhodopsin. This is the transmembrane protein which, when photoexcited, initiates the visual transduction cascade. Defects in this gene are also one of the causes of congenital stationary night blindness.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: RHO\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-p, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Rhodopsin Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 39028\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P08100; Mouse: P15409; Rat: P51489\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: RHO; OPN2; Rhodopsin; Opsin-2\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 6010; Mouse: 212541; Rat: 24717\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239882318003,"sku":"BT-AP07833-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239882350771,"sku":"BT-AP07833-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239882383539,"sku":"BT-AP07833-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_3e7a0b9a-32ae-4d69-9a2f-b204ed92dacd.png?v=1769400395","url":"https:\/\/afsbio.com\/products\/rhodopsin-polyclonal-antibody-bt-ap07833","provider":"AFSBio Inc.","version":"1.0","type":"link"}