{"product_id":"rhoh-polyclonal-antibody-e-ab-61902","title":"RHOH Polyclonal Antibody - E-AB-61902","description":"\u003cp\u003eRHOH Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-61902-60, E-AB-61902-120, E-AB-61902-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: RHOH\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: RHOH; ARHH; TTF\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB, IF\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: Q15669\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a member of the Ras superfamily of guanosine triphosphate (GTP)-metabolizing enzymes. The encoded protein is expressed in hematopoietic cells, where it functions as a negative regulator of cell growth and survival. This gene may be hypermutated or misexpressed in leukemias and lymphomas. Chromosomal translocations in non-Hodgkin's lymphoma occur between this locus and B-cell CLL\/lymphoma 6 (BCL6) on chromosome 3, leading to the production of fusion transcripts. Alternative splicing in the 5' untranslated region results in multiple transcript variants that encode the same protein.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human RHOH (NP_004301.1).\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB \t1:500-1:2000   IF \t1:10-1:100\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 21kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 27kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43146215194803,"sku":"E-AB-61902-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43146215260339,"sku":"E-AB-61902-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43146215325875,"sku":"E-AB-61902-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_08271912-5a26-493c-86fa-ee9b429f8080.png?v=1710291788","url":"https:\/\/afsbio.com\/products\/rhoh-polyclonal-antibody-e-ab-61902","provider":"AFSBio Inc.","version":"1.0","type":"link"}