{"product_id":"rig-i-ddx58-rabbit-pab-a0550","title":"Rig-I\/DDX58 Rabbit pAb - A0550","description":"\u003cp\u003eRig-I\/DDX58 Rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: A0550-20, A0550-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases which are implicated in a number of cellular processes involving RNA binding and alteration of RNA secondary structure. This gene encodes a protein containing RNA helicase-DEAD box protein motifs and a caspase recruitment domain (CARD). It is involved in viral double-stranded (ds) RNA recognition and the regulation of the antiviral innate immune response. Mutations in this gene are associated with Singleton-Merten syndrome 2.\u003c\/p\u003e\n\n\u003cp\u003eCategory: Polyclonal Antibodies\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eCross-reactivity: Human, Rat\u003c\/p\u003e\n\n\u003cp\u003eProtein Weight: 107kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved Molecular Weight: 107kDa\/\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide\u003c\/p\u003e\n\n\u003cp\u003eSpecies: Human\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 23586\u003c\/p\u003e\n\n\u003cp\u003eSWISS: O95786\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: RIG1; DDX58; RIG-I; RLR-1; SGMRT2; Rig-I\/DDX58\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003ePurity: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20℃. Avoid freeze \/ thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eRecommended Dilutions: WB, 1:2000 - 1:4000 ELISA, Recommended starting concentration is 1 μg\/mL. Please optimize the concentration based on your specific assay requirements.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Epigenetics Nuclear Signaling, Immunology Inflammation, Toll-like Receptor Signaling Pathway.\u003c\/p\u003e\n\n\u003cp\u003eNCBI Alias: RIGI\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"20uL","offer_id":45189442502835,"sku":"A0550-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"100uL","offer_id":45189442535603,"sku":"A0550-100","price":417.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_39a2f309-45cb-4a5f-bfc1-00c73664d84b.png?v=1766427338","url":"https:\/\/afsbio.com\/products\/rig-i-ddx58-rabbit-pab-a0550","provider":"AFSBio Inc.","version":"1.0","type":"link"}