{"product_id":"rip3-phospho-ser227-rabbit-pab-es13390","title":"RIP3 (phospho-Ser227) rabbit pAb - ES13390","description":"\u003cp\u003eRIP3 (phospho-Ser227) rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES13390-50, ES13390-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The product of this gene is a member of the receptor-interacting protein (RIP) family of serine\/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor. [provided by RefSeq, Jul 2008],\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: Receptor-interacting serine\/threonine-protein kinase 3 (EC 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3)\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; ELISA; IHC\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthesized phosho peptide around human RIP3 (Ser227)\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 56-70kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 11035\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: Q9Y572\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Cytoplasm, cytosol. Nucleus. Mainly cytoplasmic. Present in the nucleus in response to influenza A virus (IAV) infection.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202403852467,"sku":"ES13390-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202403885235,"sku":"ES13390-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_b77f5215-0715-45bc-bd07-da0bea0c6d7b.png?v=1767128433","url":"https:\/\/afsbio.com\/products\/rip3-phospho-ser227-rabbit-pab-es13390","provider":"AFSBio Inc.","version":"1.0","type":"link"}