{"product_id":"rip3-phospho-ser227-rabbit-polyclonal-antibody-bt-ap12295","title":"RIP3 (Phospho-Ser227) Rabbit Polyclonal Antibody - BT-AP12295","description":"\u003cp\u003eRIP3 (Phospho-Ser227) Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP12295-20, BT-AP12295-50, BT-AP12295-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The product of this gene is a member of the receptor-interacting protein (RIP) family of serine\/threonine protein kinases| and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm| and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex| and can induce apoptosis and weakly activate the NF-kappaB transcription factor.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Cancer; Cell biology; Immunology; Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: RIPK3\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: RIP3\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q9Y572; Mouse: Q9QZL0; Rat: Q9Z2P5\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: RIP3;Ser227; Receptor-interacting serine\/threonine-protein kinase 3; EC 2.7.11.1; RIP-like protein kinase 3; Receptor-interacting protein 3; RIP-3\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 11035; Rat: 246240\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239018356915,"sku":"BT-AP12295-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239018389683,"sku":"BT-AP12295-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239018422451,"sku":"BT-AP12295-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_1773ed61-2ddc-4d6c-8e69-1b60bb0bc297.png?v=1769387998","url":"https:\/\/afsbio.com\/products\/rip3-phospho-ser227-rabbit-polyclonal-antibody-bt-ap12295","provider":"AFSBio Inc.","version":"1.0","type":"link"}