{"product_id":"rip3-polyclonal-antibody-e-ab-60962","title":"RIP3 Polyclonal Antibody - E-AB-60962","description":"\u003cp\u003eRIP3 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-60962-60, E-AB-60962-120, E-AB-60962-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: RIP3\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: RIPK3; RIP3\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Cell Biology, Immunology, Signal Transduction\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: IHC, IF\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: Q9Y572\u003c\/p\u003e\n\n\u003cp\u003eBackground: The product of this gene is a member of the receptor-interacting protein (RIP) family of serine\/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human RIP3 (NP_006862.2).\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: IHC \t1:50-1:200   IF \t1:50-1:200\u003c\/p\u003e\n\n \n\n \n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43136835158195,"sku":"E-AB-60962-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43136835223731,"sku":"E-AB-60962-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43136835256499,"sku":"E-AB-60962-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_d104e982-3ed4-487f-a0e5-aeb428f383d3.png?v=1709992464","url":"https:\/\/afsbio.com\/products\/rip3-polyclonal-antibody-e-ab-60962","provider":"AFSBio Inc.","version":"1.0","type":"link"}