{"product_id":"rita1-polyclonal-antibody-e-ab-19212","title":"RITA1 Polyclonal Antibody - E-AB-19212","description":"\u003cp\u003eRITA1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-19212-60, E-AB-19212-120, E-AB-19212-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: RITA1\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: C12orf52 ; Chromosome 12 open reading frame 52 ; RBPJ interacting and tubulin associated 1; RBPJ interacting and tubulin associated protein 1; RBPJ-interacting and tubulin-associated protein; RITA; RITA\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Developmental biology, Neuroscience, Signal transduction, Stem cells\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplication: IHC, ELISA\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: Q96K30\u003c\/p\u003e\n\n\u003cp\u003eBackground: Tubulin-binding protein that acts as a negative regulator of Notch signaling pathway. Shuttles between the cytoplasm and the nucleus and mediates the nuclear export of RBPJ\/RBPSUH, thereby preventing the interaction between RBPJ\/RBPSUH and NICD product of Notch proteins (Notch intracellular domain), leading to down-regulate Notch-mediated transcription. May play a role in neurogenesis.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1.02 mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Fusion protein of human RITA1\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Antigen affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: IHC 1:50-1:200, ELISA 1:5000-1:10000\u003c\/p\u003e\n\n \n\n \n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43133389635763,"sku":"E-AB-19212-60","price":200.2,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43133389668531,"sku":"E-AB-19212-120","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43133389701299,"sku":"E-AB-19212-200","price":558.6,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_6b8b3729-2525-4c4d-a2db-ff2be3c1c9f0.png?v=1709898377","url":"https:\/\/afsbio.com\/products\/rita1-polyclonal-antibody-e-ab-19212","provider":"AFSBio Inc.","version":"1.0","type":"link"}