{"product_id":"rm45-polyclonal-antibody-bt-ap13847","title":"RM45 Polyclonal Antibody - BT-AP13847","description":"\u003cp\u003eRM45 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP13847-20, BT-AP13847-50, BT-AP13847-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Alternative splicing results in multiple transcript variants. Pseudogenes corresponding to this gene are found on chromosomes 2p and 17q.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Epigenetics and nuclear signaling; Metabolism; Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: MRPL45\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: 39S ribosomal protein L45, mitochondrial\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q9BRJ2; Mouse: Q9D0Q7\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: 39S ribosomal protein L45, mitochondrial;L45mt;MRP-L45\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 84311\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239323132083,"sku":"BT-AP13847-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239323164851,"sku":"BT-AP13847-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239323197619,"sku":"BT-AP13847-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_cc46d94a-83ac-493d-a0eb-a8aa0e616bea.png?v=1769393042","url":"https:\/\/afsbio.com\/products\/rm45-polyclonal-antibody-bt-ap13847","provider":"AFSBio Inc.","version":"1.0","type":"link"}