{"product_id":"rnf170-polyclonal-antibody-e-ab-91063","title":"RNF170 Polyclonal Antibody - E-AB-91063","description":"\u003cp\u003eRNF170 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-91063-60, E-AB-91063-120, E-AB-91063-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: RNF170\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: RNF170; ADSA; SNAX1\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplication: WB\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: Q96K19\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a RING domain-containing protein that resides in the endoplasmic reticulum (ER) membrane. This protein functions as an E3 ubiquitin ligase and mediates ubiquitination and processing of inositol 1, 4, 5-trisphosphate (IP3) receptors via the ER-associated protein degradation pathway. It is recruited to the activated IP3 receptors by the ERLIN1\/ERLIN2 complex to which it is constitutively bound. Mutations in this gene are associated with autosomal dominant sensory ataxia. Alternatively spliced transcript variants have been found for this gene.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human RNF170\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.01% thiomersal, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-1:2000\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 13kDa\/18kDa\/20kDa\/22kDa\/26kDa\/29kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved MW: 30kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43148772573363,"sku":"E-AB-91063-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43148772606131,"sku":"E-AB-91063-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43148772638899,"sku":"E-AB-91063-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_44a94037-e883-4e7f-86a6-5eb74fd48861.png?v=1710329685","url":"https:\/\/afsbio.com\/products\/rnf170-polyclonal-antibody-e-ab-91063","provider":"AFSBio Inc.","version":"1.0","type":"link"}