{"product_id":"rnf6-polyclonal-antibody-bt-ap13870","title":"RNF6 Polyclonal Antibody - BT-AP13870","description":"\u003cp\u003eRNF6 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP13870-20, BT-AP13870-50, BT-AP13870-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene contains a RING-H2 finger motif. Deletions and mutations in this gene were detected in esophageal squamous cell carcinoma (ESCC), suggesting that this protein may be a potential tumor suppressor. Studies of the mouse counterpart suggested a role of this protein in the transcription regulation that controls germinal differentiation. Multiple alternatively spliced transcript variants encoding the same protein are observed.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Cell biology\u003c\/p\u003e \n\n\u003cp\u003eTarget Protein: RNF6\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: E3 ubiquitin-protein ligase RNF6\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q9Y252; Mouse: Q9DBU5\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: E3 ubiquitin-protein ligase RNF6;EC 6.3.2.-\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 6049\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239324573875,"sku":"BT-AP13870-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239324606643,"sku":"BT-AP13870-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239324639411,"sku":"BT-AP13870-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_d1043a1a-a5a5-4c41-93ae-11e4b2703030.png?v=1769393060","url":"https:\/\/afsbio.com\/products\/rnf6-polyclonal-antibody-bt-ap13870","provider":"AFSBio Inc.","version":"1.0","type":"link"}