{"product_id":"rnf7-polyclonal-antibody-e-ab-61633","title":"RNF7 Polyclonal Antibody - E-AB-61633","description":"\u003cp\u003eRNF7 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-61633-60, E-AB-61633-120, E-AB-61633-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: RNF7\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: RNF7; CKBBP1; ROC2; SAG\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Metabolism\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplication: IF\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n \n\n\u003cp\u003eUNIProt ID: Q9UBF6\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a highly conserved ring finger protein. It is an essential subunit of SKP1-cullin\/CDC53-F box protein ubiquitin ligases, which are a part of the protein degradation machinery important for cell cycle progression and signal transduction. This protein interacts with, and is a substrate of, casein kinase II (CSNK2A1\/CKII). The phosphorylation of this protein by CSNK2A1 has been shown to promote the degradation of IkappaBalpha (CHUK\/IKK-alpha\/IKBKA) and p27Kip1(CDKN1B). Alternatively spliced transcript variants encoding distinct isoforms have been reported.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human RNF7 (NP_055060.1).\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: IF 1:20-1:50\u003c\/p\u003e\n\n \n\n \n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43136852721843,"sku":"E-AB-61633-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43136852754611,"sku":"E-AB-61633-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43136852787379,"sku":"E-AB-61633-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_643a32d0-24c5-45db-8ad3-871dfd84f16d.png?v=1709992733","url":"https:\/\/afsbio.com\/products\/rnf7-polyclonal-antibody-e-ab-61633","provider":"AFSBio Inc.","version":"1.0","type":"link"}