{"product_id":"ro60-rabbit-pab-es7287","title":"RO60 rabbit pAb - ES7287","description":"\u003cp\u003eRO60 rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES7287-50, ES7287-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: disease:Sera from patients with systemic lupus erythematosus (SLE) often contain antibodies that react with the normal cellular SSA2 protein as if this antigen was foreign., function:RNA-binding protein that binds to several small cytoplasmic RNA molecules known as Y RNAs. May stabilize these RNAs from degradation., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Belongs to the Ro 60 kDa family., similarity:Contains 1 TROVE domain., subunit:Found in a complex with PUF60 and Y5 RNA. Interacts with RIP11.,\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: TROVE2; RO60; SSA2; 60 kDa SS-A\/Ro ribonucleoprotein; 60 kDa Ro protein; 60 kDa ribonucleoprotein Ro; RoRNP; Ro 60 kDa autoantigen; Sjoegren syndrome antigen A2; Sjoegren syndrome type A antigen; SS-A; TROVE domain family member 2\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; IHC\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-2000; IHC-p 1:50-300\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Rat; Mouse;\u003c\/p\u003e \n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human TROVE2. AA range:311-360\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 70kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 6738\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: P10155\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Cytoplasm. Localized in cytoplasmic mRNP granules containing untranslated mRNAs.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202336088243,"sku":"ES7287-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202336121011,"sku":"ES7287-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_a8377866-f24d-4777-8737-247e2e432cdb.png?v=1767126871","url":"https:\/\/afsbio.com\/products\/ro60-rabbit-pab-es7287","provider":"AFSBio Inc.","version":"1.0","type":"link"}