{"product_id":"rpa2-a17-polyclonal-antibody-bs1692","title":"RPA2 (A17) Polyclonal Antibody-BS1692","description":"\u003cp\u003eRPA2 (A17) Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS1692-50, BS1692-100\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P15927\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC, IF\u003c\/p\u003e \n\n\u003cp\u003eBackground: RPA is a major damage-recognition protein involved in the early stages of nucleotide excision repair. It can also play a role in telomere maintenance. The C-terminus of RPA 32 can specfically intereact with the DNA repair enzyme UNG2 and repair factors XPA and Rad52, each of which functions in a different repair pathway. In addition, RPA 32 binds specifically to the SH2 domain of Stat3 in vivo, and overexpression of RPA 32 corresponds to the augmented growth factor-stimulated tyrosine phosphorylation and transcription activities of Stat3.\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: RPA2 (A17) polyclonal antibody detects endogenous levels of RPA2 protein.\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot (WB) analysis of RPA2 (A17) pAb at 1:500 dilution\u003cbr\u003e\nLane 1: H1792 whole cell lysate (40ug)\u003cbr\u003e\nLane 2: EC9706 whole cell lysate (40ug)\u003cbr\u003e\nLane 3: A549 whole cell lysate (40ug)\u003cbr\u003e\nLane 4: SGC7901 whole cell lysate (40ug)\u003cbr\u003e\nLane 5: HCT116 whole cell lysate (40ug)\u003cbr\u003e\nLane 6: PMVEC whole cell lysate (40ug)\u003cbr\u003e\nLane 7: 3T3-L1 whole cell lysate (40ug), Immunohistochemistry (IHC) analyzes of RPA2 (A17) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.\u003c\/p\u003e \n\n\u003cp\u003eBioworld Molecular Weight: ~ 32 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: Replication protein A 32 kDa subunit; RP-A p32; RF-A protein 2; RPA2; REPA2; RPA32; RPA34\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide, corresponding to the N-terminus of Human RPA2.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42953213739187,"sku":"BS1692-50","price":254.38,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42953213771955,"sku":"BS1692-100","price":442.75,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_a7080d0b-753b-467b-900f-97e334bde773.jpg?v=1705056893","url":"https:\/\/afsbio.com\/products\/rpa2-a17-polyclonal-antibody-bs1692","provider":"AFSBio Inc.","version":"1.0","type":"link"}