{"product_id":"rrm2-polyclonal-antibody-bs7520","title":"RRM2 Polyclonal Antibody-BS7520","description":"\u003cp\u003eRRM2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS7520-50, BS7520-100\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: P31350\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC-P IF\/ICC IP,\u003c\/p\u003e \n\n\u003cp\u003eAll Applications: WB\t 1:500 - 1:1000\u003cbr\u003e\nIHC-P\t 1:50 - 1:200\u003cbr\u003e\nIF\/ICC\t 1:50 - 1:200\u003cbr\u003e\nIP  1:50 - :1200\u003c\/p\u003e\n\n\u003cp\u003eBackground: Ribonucleotide reductase M2 subunit is one of two subunits that constitute ribonucleotide reductase, the enzyme that catalyzes the conversion of ribonucleotide 5'-diphosphates into 2'-deoxyribonucleotides, a rate-limiting step in the production of 2'-deoxyribonucleoside 5'-diphosphates (dNTP) required for DNA synthesis and repair that is required for DNA synthesis and repair.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: RRM2 polyclonal antibody detects endogenous levels of RRM2 protein.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 45 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot analysis of extracts of HeLa cells, using RRM2 antibody at 1:1000 dilution., Immunohistochemistry analysis of paraffin-embedded human colon carcinoma using RRM2 pAb at dilution of 1:100 (40x lens)., Immunofluorescence analysis of U2OS cells using RRM2 pAb at dilution of 1:100 (40x lens)., Immunoprecipitation analysis of 200 μg extracts of HeLa cells using 1 μg RRM2 antibody. Western blot was performed from the immunoprecipitate using RRM2 antibody at a dilution of 1:1000.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: R2; Ribonucleoside-diphosphate reductase subunit M2; Ribonucleotide reductase M2 subunit; Ribonucleotide reductase small chain; Ribonucleotide reductase small subunit; RIR2_HUMAN; RR2; RR2M; RRM2\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-70 of human RRM2 (NP_001025.1).\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":43044058267827,"sku":"BS7520-50","price":342.59,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":43044058300595,"sku":"BS7520-100","price":589.65,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_62f00ab5-d082-446c-90f4-86bfc59edda4.jpg?v=1707739243","url":"https:\/\/afsbio.com\/products\/rrm2-polyclonal-antibody-bs7520","provider":"AFSBio Inc.","version":"1.0","type":"link"}