{"product_id":"rsk2-monoclonal-antibody-mb67015","title":"RSK2 Monoclonal Antibody - MB67015","description":"\u003cp\u003eRSK2 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μl, 100μl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: MB67015-50, MB67015-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: Serine\/threonine-protein kinase that acts downstream of ERK (MAPK1\/ERK2 and MAPK3\/ERK1) signaling and mediates mitogenic and stress-induced activation of the transcription factors CREB1, ETV1\/ER81 and NR4A1\/NUR77, regμlates translation through RPS6 and EIF4B phosphorylation, and mediates cellμlar proliferation, survival, and differentiation by modμlating mTOR signaling and repressing pro-apoptotic function of BAD and DAPK1.\u003c\/p\u003e\n\n\u003cp\u003eCategory: Primary Antibody\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: ISPK1, MAPKAPK1B, RSK2, Ribosomal protein S6 kinase alpha-3, S6K-alpha-3, 90 kDa ribosomal protein S6 kinase 3, p90-RSK 3, p90RSK3, Insμlin-stimμlated protein kinase 1, ISPK-1, MAP kinase-activated protein kinase 1b, MAPK-activated protein kinase 1b, MAPKAP kinase 1b, MAPKAPK-1b, Ribosomal S6 kinase 2, RSK-2, pp90RSK2\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodification\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human RSK2. The exact sequence is proprietary.\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB (1\/500 - 1\/1000)\u003c\/p\u003e\n\n\u003cp\u003ePurification: This antibody is purified through a protein G column.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: Recognizes endogenous levels of RSK2 protein.\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: ~ 83 kDa\u003c\/p\u003e\n\n\u003cp\u003ePathway: Regμlation of Apoptosis, Cell Cycle G2 M DNA Damage Signaling Pathway, G Protein-coupled Receptors Signaling to MAPK Erk, MAPK Erk in Growth and Differentiation Pathway, Inhibition of Apoptosis, Regμlation of Microtubμle Dynamics, Mitochondrial Control of Apoptosis, Translational Contral elF4 and p70 S6 Kinase, MTOR signaling.\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSwissProt: P51812\u003c\/p\u003e\n\n\u003cp\u003eProduct: Mouse IgG1. Liquid in PBS, pH 7.3, 30% glycerol, and 0.01% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"50μl","offer_id":45946428096691,"sku":"MB67015-50","price":274.5,"currency_code":"CAD","in_stock":true},{"title":"100μl","offer_id":45946428129459,"sku":"MB67015-100","price":457.5,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/Bioworld_Antibody_Image_6ca33534-2486-4e91-ac84-9e0d75778258.jpg?v=1788363539","url":"https:\/\/afsbio.com\/products\/rsk2-monoclonal-antibody-mb67015","provider":"AFSBio Inc.","version":"1.0","type":"link"}