{"product_id":"rtn3-monoclonal-antibody-bt-mca4013","title":"RTN3 Monoclonal Antibody - BT-MCA4013","description":"\u003cp\u003eRTN3 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA4013-50, BT-MCA4013-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: RTN3, reticulon 3. The reticulons are a group of highly conserved genes with preferential expression in neuroendocrine tissues. RTN3 may be involved in membrane trafficking in the early secretory pathway. Inhibits BACE1 activity and amyloid precursor protein processing. May induce caspase-8 cascade and apoptosis. May favor BCL2 translocation to the mitochondria upon endoplasmic reticulum stress. In case of enteroviruses infection, RTN3 may be involved in the viral replication or pathogenesis. There are 5 isoforms.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Cell Biology, Signal Transduction, Metabolism, Cancer\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: RTN3\u003c\/p\u003e\n\n\u003cp\u003eApplications: IHC\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 10A8\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG2a\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: RTN3\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of RTN3 expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Ascitic fluid containing 0.03% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 113kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: O95197\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: HAP, ASYIP, NSPL2, NSPLII, RTN3-A1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 10313\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238639919283,"sku":"BT-MCA4013-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238639952051,"sku":"BT-MCA4013-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_4c4b0fbe-7ed0-4336-ad6d-e905a57ab501.png?v=1769383318","url":"https:\/\/afsbio.com\/products\/rtn3-monoclonal-antibody-bt-mca4013","provider":"AFSBio Inc.","version":"1.0","type":"link"}