{"product_id":"rubcn-monoclonal-antibody-bt-mca4352","title":"RUBCN Monoclonal Antibody - BT-MCA4352","description":"\u003cp\u003eRUBCN Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA4352-50, BT-MCA4352-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a negative regulator of autophagy and endocytic trafficking and controls endosome maturation. This protein contains two conserved domains, an N-terminal RUN domain and a C-terminal DUF4206 domain. The RUN domain is involved in Ras-like GTPase signaling, and the DUF4206 domain contains a diacylglycerol (DAG) binding-like motif. Mutation in this gene results in deletion of the DAG binding-like motif and causes a recessive ataxia. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Others\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: RUBCN\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 4F5B5\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: RUBCN\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Purified recombinant fragment of human NR2C2 (AA: 62-356) expressed in E. Coli.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Purified antibody in PBS with 0.05% sodium azide\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 108.6kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Q92622\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: SCAR15, RUBICON, KIAA0226\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 9711\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238378496179,"sku":"BT-MCA4352-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238378528947,"sku":"BT-MCA4352-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_b81167e6-c349-46d2-b531-23550b399b54.png?v=1769379507","url":"https:\/\/afsbio.com\/products\/rubcn-monoclonal-antibody-bt-mca4352","provider":"AFSBio Inc.","version":"1.0","type":"link"}