{"product_id":"runx1-monoclonal-antibody-bt-mca3699","title":"RUNX1 Monoclonal Antibody - BT-MCA3699","description":"\u003cp\u003eRUNX1 Monoclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Number: BT-MCA3699-50, BT-MCA3699-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq) Tissue specificity: Expressed in all tissues examined except brain and heart. Highest levels in thymus, bone marrow and peripheral blood.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Neuroscience\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: RUNX1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eClonality: Monoclonal\u003c\/p\u003e\n\n\u003cp\u003eClone ID: 2B5\u003c\/p\u003e\n\n\u003cp\u003eHost: Mouse\u003c\/p\u003e\n\n\u003cp\u003eIsotype: Mouse IgG1\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: RUNX1\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthesized peptide of human RUNX1.\u003c\/p\u003e\n\n\u003cp\u003eStorage: 4°C|-20°C for long term storage\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Ascitic fluid containing 0.03% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 55kDa\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Q01196\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: AML1, CBFA2, EVI-1, AMLCR1, PEBP2aB, AML1-EVI-1, RUNX1\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 861\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"50μL","offer_id":45238608822451,"sku":"BT-MCA3699-50","price":308.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45238608855219,"sku":"BT-MCA3699-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_ff73eab7-d9ad-4480-ad46-53d284ff2f3c.png?v=1769383031","url":"https:\/\/afsbio.com\/products\/runx1-monoclonal-antibody-bt-mca3699","provider":"AFSBio Inc.","version":"1.0","type":"link"}