{"product_id":"runx1-polyclonal-antibody-bt-ap08058","title":"RUNX1 Polyclonal Antibody - BT-AP08058","description":"\u003cp\u003eRUNX1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP08058-20, BT-AP08058-50, BT-AP08058-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by CBF2alpha (runt related transcription factor 1, RUNX1) represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for CBF2alpha.\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Neuroscience\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: RUNX1\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: RUNX1 Antibody\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight (Da): 48797\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: Q01196; Mouse: Q03347; Rat: Q63046\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: RUNX1; AML1; CBFA2; Runt-related transcription factor 1; Acute myeloid leukemia 1 protein; Core-binding factor subunit alpha-2; CBF-alpha-2; Oncogene AML-1; Polyomavirus enhancer-binding protein 2 alp\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 861; Mouse: 12394; Rat: 50662\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239893262515,"sku":"BT-AP08058-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239893295283,"sku":"BT-AP08058-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239893328051,"sku":"BT-AP08058-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_be06708d-3bd2-4b1c-bbb7-ce16cac1557a.png?v=1769400564","url":"https:\/\/afsbio.com\/products\/runx1-polyclonal-antibody-bt-ap08058","provider":"AFSBio Inc.","version":"1.0","type":"link"}