{"product_id":"rxfp1-rabbit-polyclonal-antibody-es11633","title":"RXFP1 Rabbit Polyclonal Antibody - ES11633","description":"\u003cp\u003eRXFP1 Rabbit Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES11633-50, ES11633-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: approximately 7-10 business days, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene encodes a member of the leucine-rich repeat-containing subgroup of the G protein-coupled 7-transmembrane receptor superfamily. The encoded protein plays a critical role in sperm motility, pregnancy and parturition as a receptor for the protein hormone relaxin. Decreased expression of this gene may play a role in endometriosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011],\u003c\/p\u003e \n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthesized peptide derived from human protein . at AA range: 240-320\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eTarget: RXFP1,\u003c\/p\u003e \n\n\u003cp\u003eSpecificity: RXFP1 Polyclonal Antibody detects endogenous levels of protein.\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-2000 ELISA 1:5000-20000\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml,\u003c\/p\u003e \n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eExpression: Expressed in the brain, kidney, testis, placenta, uterus, ovary, adrenal, prostate, skin and heart. Not detected in spleen.\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 83kD\u003c\/p\u003e\n\n\u003cp\u003eFields: Neuroactive ligand-receptor interaction, Relaxin signaling pathway\u003c\/p\u003e\n\n\u003cp\u003eFunction: Receptor for relaxins. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. Binding of the ligand may also activate a tyrosine kinase pathway that inhibits the activity of a phosphodiesterase that degrades cAMP. Similarity: Belongs to the G-protein coupled receptor 1 family. Similarity: Contains 1 LDL-receptor class A domain. Similarity: Contains 10 LRR (leucine-rich) repeats. Tissue Specificity: Expressed in the brain, kidney, testis, placenta, uterus, ovary, adrenal, prostate, skin and heart. Not detected in spleen.\u003c\/p\u003e \n\n\u003cp\u003eSubcellular Location: Cell membrane, Multi-pass membrane protein\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eGene Name: RXFP1, LGR7\u003c\/p\u003e\n\n\u003cp\u003eProtein Name: Relaxin receptor 1, Leucine-rich repeat-containing G-protein coupled receptor 7, Relaxin family peptide receptor 1\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 59350\u003c\/p\u003e\n\n\u003cp\u003eHuman SwissProt Number: Q9HBX9\u003c\/p\u003e\n\n\u003cp\u003eMouse SwissProt Number: Q6R6I7\u003c\/p\u003e\n\n\u003cp\u003eRat SwissProt Number: Q6R6I6\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Biotechnology","offers":[{"title":"50μL","offer_id":45825499889843,"sku":"ES11633-50","price":186.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45825499922611,"sku":"ES11633-100","price":372.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/elk-biotechnology-logo-product.jpg?v=1786476023","url":"https:\/\/afsbio.com\/products\/rxfp1-rabbit-polyclonal-antibody-es11633","provider":"AFSBio Inc.","version":"1.0","type":"link"}