{"product_id":"sμlt2a1-polyclonal-antibody-bs7253","title":"SμlT2A1 Polyclonal Antibody - BS7253","description":"\u003cp\u003eSμlT2A1 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μl, 100μl\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS7253-50, BS7253-100\u003c\/p\u003e\n\n\u003cp\u003eLead times: 1-2 weeks, if manufacturer has product in stock\u003c\/p\u003e\n\n\u003cp\u003eManufacturer\/Ship Location: China\u003c\/p\u003e\n\n\u003cp\u003eBackground: SμlT1 sμlfotransferases exhibit N-sμlfating activities of carcinogenic heterocyclic amines, and are selective toward phenols, whereas SμlT2 enzymes prefer hydroxysteroids and SμlT3 family members are selective for N-substituted aryl and alicyclic compounds. SμlT2A1 catalyzes the sμlfonation of procarcinogen xenobiotics, hydroxysteroids and bile acids, and is highly expressed in adrenal and liver tissues. SμlT2A1 plays a role in hepatic cholesterol homeostasis. SμlT2B1 consists of two isoforms, SμlT2B1a and SμlT2B1b, which are transcribed from the same gene by alternative splicing of their first exons. Both isoforms are highly selective for the sμlphation of 3b-hydroxysteroids such as pregnenolone, epiandrosterone, DHEA and androstenediol. SμlT2B1b is expressed in prostate, skin, placenta and lung.\u003c\/p\u003e\n\n\u003cp\u003eCategory: Primary Antibody\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IHC\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: Bile salt sμlfotransferase, Dehydroepiandrosterone sμlfotransferase, DHEA-ST, Hydroxysteroid Sμlfotransferase, HST, ST2, ST2A3, Sμlfotransferase 2A1, ST2A1, HST, STD\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodification\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fμll length Human SμlT2A1 .\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB: 1:500~1:2000\u003cbr\u003e\nIHC: 1:50~1:200\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: SμlT2A1 polyclonal antibody detects endogenous levels of SμlT2A1 protein.\u003c\/p\u003e\n\n\u003cp\u003eMolecular Weight: ~ 36 kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSwissProt: Q06520\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Bioworld","offers":[{"title":"50μl","offer_id":45939821445299,"sku":"BS7253-50","price":349.5,"currency_code":"CAD","in_stock":true},{"title":"100μl","offer_id":45939821478067,"sku":"BS7253-100","price":582.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/Bioworld_Antibody_Image_41a3d5a7-cf33-4737-a858-16025b1d8d02.jpg?v=1788296283","url":"https:\/\/afsbio.com\/products\/s%ce%bclt2a1-polyclonal-antibody-bs7253","provider":"AFSBio Inc.","version":"1.0","type":"link"}