{"product_id":"s100a7-psoriasin-polyclonal-antibody-e-ab-92448","title":"S100A7\/Psoriasin Polyclonal Antibody - E-AB-92448","description":"\u003cp\u003eS100A7\/Psoriasin Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 60μL, 120μL, 200μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: E-AB-92448-60, E-AB-92448-120, E-AB-92448-200\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eAbbreviation: S100A7\/Psoriasin\u003c\/p\u003e\n\n\u003cp\u003eTarget Synonym: S100A7; PSOR1; S100A7c\u003c\/p\u003e\n\n\u003cp\u003eResearch Areas: Tags \u0026amp; Cell Markers,Signal Transduction,Cancer\u003c\/p\u003e\n\n\u003cp\u003eConjugation: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eSpecies Reactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplication: IHC\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eUNIProt ID: P31151\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and\/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein differs from the other S100 proteins of known structure in its lack of calcium binding ability in one EF-hand at the N-terminus. The protein is overexpressed in hyperproliferative skin diseases, exhibits antimicrobial activities against bacteria and induces immunomodulatory activities.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1mg\/mL\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant fusion protein of human S100A7\/Psoriasin\u003c\/p\u003e\n\n\u003cp\u003eBuffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3.\u003c\/p\u003e\n\n\u003cp\u003ePurification Method: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eDilution: IHC 1:50-1:200\u003c\/p\u003e\n\n\u003cp\u003eCalculated MW: 11kDa\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C\/One year. Avoid freeze \/ thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eShipping: Ice bag\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Elabscience","offers":[{"title":"60μL","offer_id":43144020885683,"sku":"E-AB-92448-60","price":280.0,"currency_code":"CAD","in_stock":true},{"title":"120μL","offer_id":43144020918451,"sku":"E-AB-92448-120","price":448.0,"currency_code":"CAD","in_stock":true},{"title":"200μL","offer_id":43144020951219,"sku":"E-AB-92448-200","price":742.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/logo_new_4b3f4a71-eb7d-4e9f-b92e-d3b6e1dc6d37.png?v=1710245402","url":"https:\/\/afsbio.com\/products\/s100a7-psoriasin-polyclonal-antibody-e-ab-92448","provider":"AFSBio Inc.","version":"1.0","type":"link"}