{"product_id":"s10ac-polyclonal-antibody-bt-ap13997","title":"S10AC Polyclonal Antibody - BT-AP13997","description":"\u003cp\u003eS10AC Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BT-AP13997-20, BT-AP13997-50, BT-AP13997-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and\/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein is proposed to be involved in specific calcium-dependent signal transduction pathways and its regulatory effect on cytoskeletal components may modulate various neutrophil activities. The protein includes an antimicrobial peptide which has antibacterial activity.\u003c\/p\u003e \n\n\u003cp\u003eResearch Areas: Immunology; Signal transduction\u003c\/p\u003e\n\n\u003cp\u003eTarget Protein: S100A12\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, ELISA\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Rat, Mouse\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eFull Product Name: Protein S100-A12\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189\u003c\/p\u003e\n\n\u003cp\u003eStorage: -20°C for 1 year\u003c\/p\u003e\n\n\u003cp\u003ePurification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.\u003c\/p\u003e\n\n\u003cp\u003eFormulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eUniProt Accession: Human: P80511\u003c\/p\u003e\n\n\u003cp\u003eSynonyms: Protein S100-A12;CGRP;Calcium-binding protein in amniotic fluid 1;CAAF1;Calgranulin-C;CAGC;Extracellular newly identified RAGE-binding protein;EN-RAGE;Migration inhibitory factor-relate\u003c\/p\u003e\n\n\u003cp\u003eGeneID: Human: 6283\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"BT Lab","offers":[{"title":"20μL","offer_id":45239333388467,"sku":"BT-AP13997-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"50μL","offer_id":45239333421235,"sku":"BT-AP13997-50","price":252.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45239333454003,"sku":"BT-AP13997-100","price":385.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_fda78d6a-543b-4f49-93ea-c9fd60e37227.png?v=1769393169","url":"https:\/\/afsbio.com\/products\/s10ac-polyclonal-antibody-bt-ap13997","provider":"AFSBio Inc.","version":"1.0","type":"link"}