{"product_id":"s7a14-rabbit-pab-es13220","title":"S7A14 rabbit pAb - ES13220","description":"\u003cp\u003eS7A14 rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: ES13220-50, ES13220-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: This gene is predicted to encode a glycosylated, cationic amino acid transporter protein with 14 transmembrane domains. This gene is primarily expressed in skin fibroblasts, neural tissue, and primary endothelial cells and its protein is predicted to mediate lysosomal uptake of cationic amino acids. Mutations in this gene are associated with autosomal recessive retinitis pigmentosa. In mice, this gene is expressed in the photoreceptor layer of the retina where its expression increases over the course of retinal development and persists in the mature retina. [provided by RefSeq, Apr 2014],\u003c\/p\u003e \n\n\u003cp\u003eAlternate Name: Probable cationic amino acid transporter (Solute carrier family 7 member 14)\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e\n\n\u003cp\u003eDilution: WB 1:500-2000\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human; Mouse\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthesized peptide derived from human S7A14 AA range: 50-100\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eClonality: Polyclonal\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003eConcentration: 1 mg\/ml\u003c\/p\u003e\n\n\u003cp\u003eObserved Band (KD): 85kD\u003c\/p\u003e\n\n\u003cp\u003eHuman Gene ID: 57709\u003c\/p\u003e\n\n\u003cp\u003eHuman SWISS Prot NO: Q8TBB6\u003c\/p\u003e\n\n\u003cp\u003eSubcellular Location: Lysosome membrane; Multi-pass membrane protein. Exhibits a punctated pattern in the cytoplasm, which partially ovelaps with lysosomes.\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ELK Bio","offers":[{"title":"50μL","offer_id":45202403328179,"sku":"ES13220-50","price":207.2,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45202403360947,"sku":"ES13220-100","price":347.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_360x_bcf32a54-547a-4f02-8ffd-42a2f3c7e0e6.png?v=1767128417","url":"https:\/\/afsbio.com\/products\/s7a14-rabbit-pab-es13220","provider":"AFSBio Inc.","version":"1.0","type":"link"}