{"product_id":"saf-b-monoclonal-antibody-ra11971","title":"SAF-B Monoclonal Antibody - RA11971","description":"SAF-B Monoclonal Antibody\n\nSize: 50μL, 100μL\n\nCatalogue Numbers: RA11971-50, RA11971-100\n\nCitations, Manuals and MSDS Available upon request.\n\nBackground: scaffold attachment factor B (SAFB) Homo sapiens This gene encodes a DNA-binding protein which has high specificity for scaffold or matrix attachment region DNA elements (S\/MAR DNA) . This protein is thought to be involved in attaching the base of chromatin loops to the nuclear matrix but there is conflicting evidence as to whether this protein is a component of chromatin or a nuclear matrix protein. Scaffold attachment factors are a specific subset of nuclear matrix proteins (NMP) that specifically bind to S\/MAR. The encoded protein is thought to serve as a molecular base to assemble a 'transcriptosome complex' in the vicinity of actively transcribed genes. It is involved in the regulation of heat shock protein 27 transcription, can act as an estrogen receptor co-repressor and is a candidate for breast tumorigenesis. This gene is arranged head-to-head with a similar gene whose product has the same functions. Multiple transcript v\n\nCondition: Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50% glycerol.\n\nStorage Instructions: -20°C\/1 year\n\nApplications: WB\n\nSpecies Cross-Reactivity: Human\n\nGeneID (Human): 6294\n\nSWISS: Q15424\n\nSource: Mouse\n\nResearch Use Only","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45118996021427,"sku":"RA11971-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45118996054195,"sku":"RA11971-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_8ab31761-d1bd-4a7f-9d56-342926e5c7c5.png?v=1773344051","url":"https:\/\/afsbio.com\/products\/saf-b-monoclonal-antibody-ra11971","provider":"AFSBio Inc.","version":"1.0","type":"link"}