{"product_id":"sarcoglycan-α-polyclonal-antibody-bs5920","title":"Sarcoglycan-α Polyclonal Antibody-BS5920","description":"\u003cp\u003eSarcoglycan-α Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS5920-50, BS5920-100\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: Alpha-sarcoglycan; Sarcoglycan α; α-Sarcoglycan; α-SG; SG-α; SGα; Alpha-SG; 50 kDa dystrophin-associated glycoprotein; 50DAG; Adhalin; Dystroglycan-2; Dystroglycan 2; Dystroglycan2; SGCA; ADL; DAG2;\u003c\/p\u003e \n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: Q16586\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human, Mouse, Rat\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB ICC IP\u003c\/p\u003e \n\n\u003cp\u003eAll Applications: WB: 1:500~1:1000\u003cbr\u003e\nICC: 1:50~1:200\u003cbr\u003e\nIP: 1:50~1:200\u003c\/p\u003e\n\n\u003cp\u003eBackground: The sarcoglycan transmembrane proteins are members of the dystrophin complex. Sarcoglycans cluster together to form a complex, which is localized in the cell membrane of skeletal, cardiac, and smooth muscle fibers. Four sarcoglycan subunit proteins, designated α-, β-, γ- and δ-sarcoglycan, form a complex on the skeletal muscle cell surface membrane. A genetic defect in any one of these proteins causes the loss or marked decrease of the whole sarcoglycan complex, which is observed in the autosomal recessive muscular dystrophy, sarcoglycanopathy. In smooth muscle, β- and δ-sarcoglycans are associated with ε-sarcoglycan, a glycoprotein homologous to α-sarcoglycan. Additionally, a complete deficiency in δ-sarcoglycan is the cause of the Syrian hamster BIO.14 cardiomyopathy.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: Sarcoglycan-α polyclonal antibody detects endogenous levels of Sarcoglycan-α protein.\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 42 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot (WB) analysis of Sarcoglycan-α pAb at 1:500 dilution\u003cbr\u003e\nLane 1: AML-12 whole cell lysate(40ug)\u003cbr\u003e\nLane 2: H9C2 whole cell lysate(40ug)\u003cbr\u003e\nLane 3: A549 whole cell lysate(40ug)\u003cbr\u003e\nLane 4: EC9706 whole cell lysate(40ug)\u003cbr\u003e\nLane 5: H1792 whole cell lysate(40ug)\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide, corresponding to amino acids 209-254 of Human Sarcoglycan-α.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42911822872755,"sku":"BS5920-50","price":260.23,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42911822905523,"sku":"BS5920-100","price":452.94,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_03a89668-4920-46f6-89de-c0351edc8899.jpg?v=1703180090","url":"https:\/\/afsbio.com\/products\/sarcoglycan-%ce%b1-polyclonal-antibody-bs5920","provider":"AFSBio Inc.","version":"1.0","type":"link"}