{"product_id":"sars-cov-2-spike-s1-rabbit-pab-a20136","title":"SARS-CoV-2 Spike S1 Rabbit pAb - A20136","description":"\u003cp\u003eSARS-CoV-2 Spike S1 Rabbit pAb\u003c\/p\u003e\n\n\u003cp\u003eSizes: 20μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: A20136-20, A20136-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an enveloped, positive-sense, single-stranded RNA virus that causes coronavirus disease 2019 (COVID-19). Virus particles include the RNA genetic material and structural proteins needed for invasion of host cells. Once inside the cell the infecting RNA is used to encode structural proteins that make up virus particles, nonstructural proteins that direct virus assembly, transcription, replication and host control and accessory proteins whose function has not been determined.~ The structural proteins of SARS-CoV-2 include the envelope protein (E), spike or surface glycoprotein (S), membrane protein (M) and the nucleocapsid protein (N). The spike glycoprotein is found on the outside of the virus particle and gives coronavirus viruses their crown-like appearance. This glycoprotein mediates attachment of the virus particle and entry into the host cell. S protein is an important target for vaccine development, antibody therapies and diagnostic antigen-based tests.\u003c\/p\u003e\n\n\u003cp\u003eCategory: Polyclonal Antibodies\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB, IF\/ICC, IP, ELISA\u003c\/p\u003e\n\n\u003cp\u003eCross-reactivity: Human, SARS-CoV-2\u003c\/p\u003e\n\n\u003cp\u003eProtein Weight: 141kDa\u003c\/p\u003e\n\n\u003cp\u003eObserved Molecular Weight: 110kDa\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Recombinant protein (or fragment)\u003c\/p\u003e\n\n\u003cp\u003eGeneID: 43740568\u003c\/p\u003e\n\n\u003cp\u003eSWISS: P0DTC2\u003c\/p\u003e\n\n\u003cp\u003eAlternate Names: spike glycoprotein; SARS-CoV-2 Spike S1\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eIsotype: IgG\u003c\/p\u003e\n\n\u003cp\u003ePurity: Affinity purification\u003c\/p\u003e\n\n\u003cp\u003eStorage: Store at -20℃. Avoid freeze \/ thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.\u003c\/p\u003e\n\n\u003cp\u003eRecommended Dilutions: WB, 1:500 - 1:1000 IF\/ICC, 1:100 - 1:500 IP, 0.5μg-4μg antibody for 200μg-400μg extracts of whole cells ELISA, 1:20000-1:80000\u003c\/p\u003e\n\n\u003cp\u003eNCBI Alias: Spike S1\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"ABclonal","offers":[{"title":"20uL","offer_id":45189378408627,"sku":"A20136-20","price":151.2,"currency_code":"CAD","in_stock":true},{"title":"100uL","offer_id":45189378441395,"sku":"A20136-100","price":417.2,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/download_c50461d6-8343-48b1-8d1c-9af0a903adfc.png?v=1766425801","url":"https:\/\/afsbio.com\/products\/sars-cov-2-spike-s1-rabbit-pab-a20136","provider":"AFSBio Inc.","version":"1.0","type":"link"}