{"product_id":"scml2-polyclonal-antibody-bs62478","title":"SCML2 Polyclonal Antibody-BS62478","description":"\u003cp\u003eSCML2 Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: BS62478-50, BS62478-100\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50µl, 100µl\u003c\/p\u003e\n\n\u003cp\u003eProduct: Rabbit IgG, 1mg\/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.4.\u003c\/p\u003e\n\n\u003cp\u003eSwiss-Prot: Q9UQR0\u003c\/p\u003e\n\n\u003cp\u003eHost: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eReactivity: Human\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB\u003c\/p\u003e \n\n\u003cp\u003eAll Applications: WB: 1:500~1000\u003c\/p\u003e\n\n\u003cp\u003eBackground: In Drosophila, the Polycomb (PcG) gene family encodes chromatin proteins that are required for the repression of homeotic loci in embryonic development. PcG proteins work in conjunction with the trithorax-group (trxG), which activate homeobox gene expression during embryonic development. SCM (sex comb on midleg) is an important Drosophila PcG protein involved in transcriptional repression. SCML2 (sex comb on midleg-like 2) is a human homolog of this Drosophila protein. SCML2 is a ubiquitously expressed protein with predominant expression in placenta, testis and thymus. Upon DNA damage, SCML2 may be phosphorylated by ATR or ATM. Due to alternative splicing, two isoforms exist for this protein.\u003c\/p\u003e\n\n\u003cp\u003ePurification and Purity: The protein was purified from E.coli and the purity is \u0026gt; 95% (by SDS-PAGE).\u003c\/p\u003e\n\n\u003cp\u003eStorage and Stability: Store at 4°C short term. Aliquot and store at -25°C long term. Avoid freeze-thaw cycles.\u003c\/p\u003e\n\n\u003cp\u003eSpecificity: SCML2 polyclonal antibody detects endogenous levels of SCML2 protein.\u003c\/p\u003e\n\n\u003cp\u003eExtra Notes: Western blot (WB) analysis of SCML2 polyclonal antibody at 1:500 dilution\u003cbr\u003e\nLaneA:HEK293T whole cell lysate\u003cbr\u003e\nLaneB:K562 whole cell lysate\u003cbr\u003e\nLaneC:A549 whole cell lysate\u003cbr\u003e\nLaneD:H1792 whole cell lysate\u003c\/p\u003e\n\n\u003cp\u003eBioworld Molecular Weight: ~ 77,93 kDa\u003c\/p\u003e\n\n\u003cp\u003eNote: For research use only, not for use in diagnostic procedure.\u003c\/p\u003e\n\n\u003cp\u003eAlternative Name: Sex comb on midleg-like protein 2; SCML2\u003c\/p\u003e\n\n\u003cp\u003eImmunogen: Synthetic peptide, corresponding to Human SCML2.\u003c\/p\u003e\n\n\u003cp\u003eConjugate: Unconjugated\u003c\/p\u003e\n\n\u003cp\u003eModification: Unmodified\u003c\/p\u003e","brand":"BioWorld","offers":[{"title":"50µl","offer_id":42910461755571,"sku":"BS62478-50","price":260.23,"currency_code":"CAD","in_stock":true},{"title":"100µl","offer_id":42910461788339,"sku":"BS62478-100","price":452.94,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/products\/thumbnail_d1447bac803ec9be_11-14-09-19-51_2cabd6c4-a009-4c87-8e3a-e6663bdd4f59.jpg?v=1703092866","url":"https:\/\/afsbio.com\/products\/scml2-polyclonal-antibody-bs62478","provider":"AFSBio Inc.","version":"1.0","type":"link"}