{"product_id":"scnba-polyclonal-antibody-ra34761","title":"SCNBA Polyclonal Antibody - RA34761","description":"\u003cp\u003eSCNBA Polyclonal Antibody\u003c\/p\u003e\n\n\u003cp\u003eSizes: 50μL, 100μL\u003c\/p\u003e\n\n\u003cp\u003eCatalogue Numbers: RA34761-50, RA34761-100\u003c\/p\u003e\n\n\u003cp\u003eCitations, Manuals and MSDS Available upon request.\u003c\/p\u003e\n\n\u003cp\u003eBackground: sodium voltage-gated channel alpha subunit 11 (SCN11A) Homo sapiens Voltage-gated sodium channels are membrane protein complexes that play a fundamental role in the rising phase of the action potential in most excitable cells. Alpha subunits, such as SCN11A, mediate voltage-dependent gating and conductance, while auxiliary beta subunits regulate the kinetic properties of the channel and facilitate membrane localization of the complex. Aberrant expression patterns or mutations of alpha subunits underlie a number of disorders. Each alpha subunit consists of 4 domains connected by 3 intracellular loops; each domain consists of 6 transmembrane segments and intra- and extracellular linkers.[supplied by OMIM, Apr 2004],\u003c\/p\u003e\n\n\u003cp\u003eCondition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.\u003c\/p\u003e\n\n\u003cp\u003eStorage Instructions: -20°C\/1 year\u003c\/p\u003e\n\n\u003cp\u003eRecommended dilutions: WB 1:500-2000 ELISA 1:5000-20000\u003c\/p\u003e\n\n\u003cp\u003eApplications: WB; ELISA\u003c\/p\u003e\n\n\u003cp\u003eSpecies Cross-Reactivity: Human; Rat; Mouse\u003c\/p\u003e\n\n\u003cp\u003eGeneID (Human): 11280\u003c\/p\u003e\n\n\u003cp\u003eProtein MW (KDa): 197\u003c\/p\u003e\n\n\u003cp\u003eSWISS: Q9UI33\u003c\/p\u003e\n\n\u003cp\u003eSource: Rabbit\u003c\/p\u003e\n\n\u003cp\u003eResearch Use Only\u003c\/p\u003e","brand":"Reed Bio","offers":[{"title":"50μL","offer_id":45120612303027,"sku":"RA34761-50","price":336.0,"currency_code":"CAD","in_stock":true},{"title":"100μL","offer_id":45120612335795,"sku":"RA34761-100","price":448.0,"currency_code":"CAD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0305\/9482\/6376\/files\/logo_adc39021-6005-478a-a34a-69059ff81965.png?v=1773368413","url":"https:\/\/afsbio.com\/products\/scnba-polyclonal-antibody-ra34761","provider":"AFSBio Inc.","version":"1.0","type":"link"}